Profile of Pulmonary Tuberculosis Treatment in Inpatients with Covid-19 History Status at Pasar Minggu Regional General Hospital in May 2020-May 2021
Article Sidebar
Main Article Content
Abstract
Pulmonary tuberculosis (TB) causes it by Mycobacterium tuberculosis, which attacks the respiratory system. During soaring cases of the Covid-19 virus outbreak, TB patients must be more aware of themselves from the episode. GTN (Global Tuberculosis Network) describes that out of 49 patients with TB status, around 26 patients suffered from pulmonary TB and were exposed to Covid-19. This study aims to determine the Profile of Pulmonary Tuberculosis Treatment in Inpatients with Covid-19 History Status at Pasar Minggu Regional General Hospital for the May 2020-May 2021 Period. This research method is a quantitative descriptive analysis with a retrospective method, taking primary data from records—patient medical. There were a total of 22 patients. Most of the sexes were male, namely 12 people (54.55%). The age of the most patients was > 60 years with a total of 6 people (27.27%), and the weight of the most patients was 38-54 kg with a capacity of 11 people (50%). The most common patients were new patients, with ten people (45.45%). The most category of treatment was Category II, with 12 people (54.54%). The pattern of KDT (Fixed-Dose Combination) category one that was most widely prescribed was the pattern of 3 4KDT tablets, three 2KDT tablets, four 4KDT tablets, and four 2KDT tablets having the same proportion of 4 prescriptions (18.18%). The most prescribed pattern of KDT category 2 was three tablets of 4KDT + 750 mg of streptomycin injection and three tablets of 2KDT + 3 tablets of ethambutol with nine prescriptions (40.90%). Drugs for Covid-19 patients are most often prescribed together with OAT, namely vitamins and minerals, as many as 56 prescriptions (42.42%).
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Alfaraj SH, Al-Tawfiq JA, Altuwaijri TA, Memish ZA. Middle East Respiratory Syndrome Coronavirus and Pulmonary Tuberculosis Coinfection: Implications for Infection Control. Intervirology. 2017;60(1–2):53–5.
Battista G, Tiberi S, Zumla A, Petersen E, Muhwa J, Wejse C, et al. International Journal of Infectious Diseases MDR / XDR-TB management of patients and contacts : Challenges facing the new decade . The 2020 clinical update by the Global Tuberculosis Network. 2020;
World Health Organization. Tuberculosis deaths rise for the first time in more than a decade due to the COVID-19 pandemic [Internet]. 2021. Available from: https://www.who.int/news/item/14-10-2021-tuberculosis-deaths-rise-for-the-first-time-in-more-than-a-decade-due-to-the-covid-19-pandemic
Soares VM, Almeida IN De, Jouca L, Figueredo DA, Paulo J, Haddad A, et al. Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais , Brazil. 2020;46(2):1–8.
Lopes AR V, Miranda SSDE, Ceccato MDASGB, Silveira MR, Resende NHDE, Carvalho WS. Evaluation of the impact of pharmaceutical care for tuberculosis patients in a Secondary Referral Outpatient Clinic, Minas Gerais, Brazil. An Acad Bras Cienc. 2017;89(4):2911–9.
Zamharira Muslim, Regita Pratiwi Mahardika Pww. Antibiotic Sensitivity Of Acute Respiratory Infection Patients In Bhayangkara Hospital Bengkulu Zamharira Muslim , Regita Pratiwi Mahardika , Putri Widelia Welkriana Poltekkes Kemenkes Bengkulu Jalan Indragiri Nomor 03 Padang Harapan Kota Bengkulu , 38225. 2020;11(1):31–40.
Gao Y, Liu M, Chen Y, Shi S, Geng J, Tian J. Association between tuberculosis and COVID-19 severity and mortality: A rapid systematic review and meta-analysis. Vol. 93, Journal of medical virology. 2021. p. 194–6.
Wan S, Xiang Y, Fang W, Zheng Y, Li B, Hu Y, et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. J Med Virol. 2020 Jul;92(7):797–806.
Tadolini et al. Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases. Eur Respir. 2020;56(1).
Siagian TH. Corona Dengan Discourse Network Analysis. J Kebijak Kesehat Indones. 2020;09(02):98–106.
Kemenkes RI. Strategi Nasional Pengendalian Tuberkulosis. Direktorat Jenderal Pengendali Penyakit dan Penyehatan Lingkung. 2014;
Kemenkes RI. Protokol Pelayanan tentang Tuberkulosis/TBC Selama Masa Pandemi Covid 19. Direktorat Jenderal Pencegahan dan Pengendalian Penyakit Kementerian Kesehatan RI. 2020.
Nurafni S, Sari N, Mulyani F. Comparison of Drug Induced Hepatotoxicity Incident of Fixed-Dose Combination and Separate Formulations Regimen for Pulmonary Tuberculosis Treatment in Hospital Sukabumi. J Phys Conf Ser. 2021 Feb;1764(1):012012.
Kurniawan AH, Tadashi Y. The Correlation Between Knowledge With Community Behavior In Antibiotic Use In Kelurahan Petukangan Utara With Home Pharmacy Care. Sanitas J Teknol Dan Seni Kesehat. 2020;10(2):139–50.
Kemenkes RI. Pedoman Nasional Pengendalian Tuberkulosis. Kementeri Kesehat Republik Indones. 2011;(Pengendalian Tuberkulosis):110.
Faizah AKNN; PON. A Mini Review : Clinically Significant Potential Drug-Drug Interactions In COVID-19 and Comorbid Therapy. Pharm Sci Res. 2020;7(Special Issue on COVID-19):23–8.
Dini C, Bianchi A. The potential role of vitamin D for prevention and treatment of tuberculosis and infectious diseases. Ann Ist Super Sanita. 2012 Sep;48(3):319–27.
Zakiyyah ER, Gurnida DA, Kartasasmita CB. Pengaruh Pemberian Vitamin C terhadap Perubahan Kadar Total Antioksidan Serum pada Penderita Tuberkulosis Paru Anak. 2014;16(2):110–4.
Seyedrezazadeh E, Ostadrahimi A, Mahboob S, Assadi Y, Ghaemmagami J, Pourmogaddam M. Effect of vitamin E and selenium supplementation on oxidative stress status in pulmonary tuberculosis patients. Respirology. 2008 Mar;13(2):294–8.
Hassanein EG, Mohamed EE, Baess AI, EL-Sayed ET, Yossef AM. The role of supplementary vitamin D in treatment course of pulmonary tuberculosis. Egypt J Chest Dis Tuberc. 2016 Jul;65(3):629–35.
Redaksi Halodoc. Ketahui Penanganan Pneumotoraks Berdasar Tingkat Keparahannya. 2019.
Pratiwi YS, Lesmana R, Setiawan S, Purba A. Autophagy dan Sarkopenia. Syifa’ Med J Kedokt dan Kesehat. 2019;10(1):31.
Davies PDO. Multi-drug resistant tuberculosis. CPD Infect. 2002;3(1):9–12.
Liu Y-C, Liao C-H, Chang C-F, Chou C-C, Lin Y-R. A Locally Transmitted Case of SARS-CoV-2 Infection in Taiwan. Vol. 382, The New England journal of medicine. 2020. p. 1070–2.
Setiadi AP, Wibowo YI, Halim S V., Brata C, Presley B, Setiawan E. Tata Laksana Terapi Pasien dengan COVID-19: Sebuah Kajian Naratif. Indones J Clin Pharm. 2020;9(1):70.
Kemenkes RI. Pedoman Tatalaksana Covid-19. 2020. 1–112 p.