Potential Antibacterial Of Leaves And Flowers Bougenvillea (Bougenvilea Glabra)

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Priyanto Dwi Nugroho
Faisal Ismail
Hana Relita

Abstract

High incidence of antibiotics resistant bacteria spurred researchers to obtain alternative antibacterial compounds. One source of potential antibacterial compounds i.e plants. Bougainvillea (Bougenvillea glabra) has been believed by the people of Indonesia to have medicinal properties, but its potential as an antibacterial has never been studied in Indonesia. The aims of this study were to determine the bioactive compounds ethanol extract of leaves and flowers of B. glabra as well as the minimum concentration of extract capable of inhibiting and killing bacteria growth. Minimum Inhibition Concentration (MIC) was done used microdilution method and Minimum Bactericidal Concentration (MBC) agar plate method. Ethanol extract of leaves and flowers of B. glabra possess antibacterial activity against pathogenic bacteria; Bacillus sp., S. aureus, Salmonella sp., E. coli, P. aeruginosa and K. pneumoniae. Salmonella, Bacillus sp., and S. aureus growth is most vulnerable (p<0.05). The antibacterial activity of leaf and flower extracts was not significantly different (p>0.05) against all test bacteria. Antibacterial potency of leaves and flowers B. glabra suspected of flavonoids, tannins, terpenoids and alkaloids

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How to Cite
1.
Nugroho P, Ismail F, Relita H. Potential Antibacterial Of Leaves And Flowers Bougenvillea (Bougenvilea Glabra). SANITAS [Internet]. 1Jun.2017 [cited 18Apr.2024];8(1):35-0. Available from: https://sanitas.e-journal.id/index.php/SANITAS/article/view/20170601-nugroho
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Author Biographies

Priyanto Dwi Nugroho, Politeknik Kesehatan Kemenkes Jakarta II

Jurusan Analisa Farmasi dan Makanan, Politeknik Kesehatan Kemenkes Jakarta II,
Jl. Raya Ragunan No.29C Pasar Minggu, DKI Jakarta, Kode Pos 12540

Faisal Ismail, Politeknik Kesehatan Kemenkes Jakarta II

Jurusan Analisa Farmasi dan Makanan, Politeknik Kesehatan Kemenkes Jakarta II,
Jl. Raya Ragunan No.29C Pasar Minggu, DKI Jakarta, Kode Pos 12540

Hana Relita, Politeknik Kesehatan Kemenkes Jakarta II

Jurusan Analisa Farmasi dan Makanan, Politeknik Kesehatan Kemenkes Jakarta II,
Jl. Raya Ragunan No.29C Pasar Minggu, DKI Jakarta, Kode Pos 12540

References

Global Burden of Disease Study 2013 Mortality and Causes of Death Collaborators. 2015. Global, regional, and national age sex specific all-cause and cause-spesific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global burden of Disease Study 2013. Lancet. 2015; 385(9963):117-171.

Madigan MT, Martinko JM, Stahl DA, Clark DP. Brock. Biology of Microorganisms14th ed. New Jersey (US):Prentice Hall. 2015

[WHO] World Health Organization. 2014. Antimicrobial resistance: global report on surveillance. Geneva (SUI).

Tukiran, Suyatno, Hidayati N. Phytochemical screening on several extracts of Bougenvillea glabra, Hibiscus rosa-sinensis L., GraptophylumpictumGriff. Prosiding Seminar Nasional Kimia. 2014;B235-245.

Sahu N, Saxena J. Phytochemical analysis of Bougenvillea glabra Choisy by FTIR and uv-vis spectroscopic analysis. Int J Pharm Sci Rev Res. 2013; 21(1):196-198.

Gupta V, George M, Joseph L, Singhal M, Singh HP. Evaluation of antibacterial activity of Bougenvillea glabra ‘snow white’ and Bougenvillea glabra ‘choisy’. J ChemPharmaceutic Res. 2009; 1(1):233-237.

Swamy K, Sudipta KM, Lokesh P, Neeld MA, Rashmi W, Bhaumik H, Darshil H, Vijay R, Kashyap SSN.. Phytochemical screening and in vitro antimicrobial activity of Bougenvilleaspectabilis flower extracts. Int J Phytomed. 2012;4(3): 375-379.

Enciso-Diaz OJ, Mendez-Guiteres A, De Jesus LH, Sharma A, Villareal ML, Taketa AC. Antibacterial activity of Bougenvillea glabra, Eucalyptus globus, Gnaphaliumattenuatum, and propolis collected in Mexico. Pharmacol Pharm. 2012;3: 433-438.

Harborne AJ. Phytochemical Methods A Guide to Modern Techniques of Plant Analysis. Springer. 1998.

Andrews JM. Determination of minimum inhibitory concentrations. J AntimicrobChemother. 2001; 48(suppl 1): 5-16.

Yilmaz MT. Minimum inhibitory and minimum bactericidal concentrations of boron compounds against several bacterial strains. Turk J Med Sci.2012; 42(2): 1423-1429.

Rani JM, Chandramohan G, Rengnathan R. Antioxidant activity, preliminary phytochemical investigation and GC-MS study of Bougenvillea glabra Choisy leaves. Int J Pharm Pharmaseutic Sci. 2012; 4(2):12-16.

Mariajancyrani J, Chandramohan G, Beevi MF, Elayaraja A. Preliminary phytochemical investigation and antioxidant activity of Bougenvillea glabra Choisy leaves. SchAcad J Biosci. 2013; 1(3): 72-75.

Eslavath R, Harikrishna V, Kosuru N, Venkateshwarlu G, Sabat M, Kanakaiah K. Phytochemical screening and TLC, uv-vis sprectophotometer study of Bougenvillea glabra. Asian J Pharm Ana. 2013; 3(3): 83-8

Sahu N, Saxena J. A comparative phytochemical analysis of Bougenvillea glabra Choisy and ‘califorina gold’. Int J Pharm Bio Sci. 2012; 3(3): 247-250.

Bungihan ME, Matias CA. Determination of the antioxidant, phytochemical and antibacterial profiles of flowers from selected ornamental plants in Nueva Vizcaya, Philippines. J AgriculSci Tech. 2013; B3: 833-841.

Perales YJ, Leysa M. Phytochemical screening and antibacterial activity of Bougenvillea glabra plant extract as potensial sources of antibacterial and resistance-modifying agents. Int Confer Life Sci Engineer. 2012; 45(25): 121-125.

Panigrahi S, Mahaprata S. Evaluation of antibacterial activity of Pongamia pinnata L., Curcuma longa L. and Menthaarvenis L. against Staphylococcus aureus. Int J Chemtech Res.2016;9(2):205-21